Antidepressants affect the elderly in largely the same way that they would affect any other population. Studies have shown that SSRIs are more effective at treating antidepressants than tricyclics. Study subjects improved 75% of the time when using tricyclics compared to 83% of the time when taking SSRIs. If older adults are unresponsive to low doses of antidepressants, higher doses may be required to achieve a therapeutic effect. Unfortunately, the failure to use effective doses in elderly patients is often the reason for a lack of clinical response and referrals made to specialists for depression incorrectly diagnosed as “treatment resistant.
Nortriptyline is the tricyclic that has been the most studied. The results of those studies show that it should be recommended as an antidepressant for older patients. It is effective in both the acute and continuation treatment of depression in the husten.xyz by: Apr 06, · SSRIs / SNRIs / atypicals: The newer generation drugs of SSRIs, SNRIs, and atypical antidepressants seem to be the most preferred options for treating depression in the elderly. These tend to have the least number of side effects and greatest upside.
Sep 20, · Previous medical research has suggested that antidepressants that affect serotonin the most have the highest bleeding risk, but this association has not been confirmed. In addition, tricyclic. 76 rows · Psychotherapy Antidepressants, such as Selective Serotonin Reuptake Inhibitors (SSRIs), .